Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA4 | P22748 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15604720 | 0.81 | LMNA (0.42) | HTTTSHRALDH1A1LMNANPSR1 | |
| SCHEMBL16181025 | 0.81 | NPC1 (0.38) | TSHRALDH1A1LMNANPSR1CRHBP | |
| SCHEMBL13123923 | 0.77 | ALDH1A1 (0.46) | HTTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL901683 | 0.74 | HTT (0.37) | HTTTSHRGFERALDH1A1LMNA | |
| SCHEMBL902864 | 0.74 | ALDH1A1 (0.38) | HTTTSHRALDH1A1LMNANPSR1 | |
| SCHEMBL902080 | 0.74 | ALDH1A1 (0.39) | HTTTSHRGFERALDH1A1LMNA | |
| SCHEMBL902099 | 0.74 | ALDH1A1 (0.33) | TSHRALDH1A1LMNANPSR1CRHBP | |
| SCHEMBL902866 | 0.72 | LMNA (0.36) | HTTTSHRGFERALDH1A1LMNA | |
| SCHEMBL902081 | 0.72 | HTT (0.35) | HTTTSHRGFERALDH1A1LMNA | |
| SCHEMBL902100 | 0.72 | HTT (0.35) | HTTTSHRGFERALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042227-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF PLANTS | PENINSULA COLLEGE OF MEDICINE AND DENTISTRY, UNIVERSITY OF EXETER (GB) | 2012-04-05 | — | — | WO | claimed |
| WO-2012042227-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF PLANTS | PENINSULA COLLEGE OF MEDICINE AND DENTISTRY, UNIVERSITY OF EXETER (GB) | 2012-04-05 | — | — | WO | disclosed |