SCHEMBL902080

SCHEMBL902080

Fc1ccccc1P(=S)(S)N1CCCCC1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.39
NPSR1 Q6W5P4 3/20 0.34
GAA P10253 3/20 0.34
KMT2A Q03164 3/20 0.33
TSHR P16473 2/20 0.33
HTT P42858 2/20 0.33
LMNA P02545 3/20 0.33
CRHBP P24387 1/20 0.33
CRHR2 Q13324 1/20 0.33
MEN1 O00255 1/20 0.31
MAPT P10636 2/20 0.30
GFER P55789 1/20 0.30
TDP1 Q9NUW8 1/20 0.30
NPC1 O15118 1/20 0.30
RAB9A P51151 1/20 0.30
HIF1A Q16665 1/20 0.30
USP2 O75604 1/20 0.30
GLA P06280 1/20 0.30
ATM Q13315 1/20 0.30
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL902864 0.79 ALDH1A1 (0.38) ALDH1A1NPSR1GAAKMT2ATSHR
SCHEMBL902099 0.79 ALDH1A1 (0.33) ALDH1A1NPSR1KMT2ATSHRLMNA
SCHEMBL902840 0.78 ALDH1A1 (0.38) ALDH1A1NPSR1GAAKMT2ATSHR
SCHEMBL902128 0.76 KMT2A (0.41) ALDH1A1GAAKMT2ATSHRHTT
Ammonia Solution, Strong SCHEMBL902862 0.74 KMT2A (0.40) ALDH1A1GAAKMT2ATSHRHTT
SCHEMBL901588 0.74 HTT (0.38) ALDH1A1NPSR1KMT2ATSHRHTT
SCHEMBL7651889 0.71 ACHE (0.35)
SCHEMBL16181025 0.64 NPC1 (0.38) ALDH1A1NPSR1KMT2ATSHRLMNA
SCHEMBL10340775 0.62 ACHE (0.35) ALDH1A1
SCHEMBL10795313 0.62 ACHE (0.40) GAAKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2012042227-A1 COMPOUNDS FOR USE IN THE TREATMENT OF PLANTS PENINSULA COLLEGE OF MEDICINE AND DENTISTRY, UNIVERSITY OF EXETER (GB) 2012-04-05 WO claimed