Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.36 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.32 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL902081 | 0.82 | HTT (0.35) | LMNAALDH1A1CRHBPCRHR2NPSR1 | |
| SCHEMBL902100 | 0.82 | HTT (0.35) | LMNAALDH1A1CRHBPCRHR2NPSR1 | |
| SCHEMBL902129 | 0.81 | KMT2A (0.34) | LMNAALDH1A1CRHBPCRHR2NPSR1 | |
| SCHEMBL901588 | 0.72 | HTT (0.38) | LMNAALDH1A1CRHBPCRHR2NPSR1 | |
| SCHEMBL901683 | 0.70 | HTT (0.37) | LMNAALDH1A1CRHBPCRHR2NPSR1 | |
| SCHEMBL31505112 | 0.67 | HTT (0.47) | LMNAHTTTSHRGFERCA12 | |
| SCHEMBL14420676 | 0.67 | TSHR (0.49) | LMNAALDH1A1HTTTSHRGFER | |
| SCHEMBL3727258 | 0.66 | ALDH1A1 (0.38) | LMNAALDH1A1NPSR1TSHRCA12 | |
| SCHEMBL14965497 | 0.63 | ESR1 (0.39) | LMNAALDH1A1NPSR1HTTCYP2B6 | |
| SCHEMBL11798793 | 0.61 | SIGMAR1 (0.50) | LMNAALDH1A1TSHRGFERCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012042227-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF PLANTS | PENINSULA COLLEGE OF MEDICINE AND DENTISTRY, UNIVERSITY OF EXETER (GB) | 2012-04-05 | — | — | WO | disclosed |