SCHEMBL9029032

SCHEMBL9029032

COc1cc(/C=C/C(=O)N2CCCCC2)ccc1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 3/20 1.00
KDM4E B2RXH2 2/20 0.78
ALDH1A1 P00352 2/20 0.78
KMT2A Q03164 1/20 0.78
ACHE P22303 9/20 0.71
FGFR1 P11362 1/20 0.68
CYP1A2 P05177 1/20 0.68
ALOX5 P09917 1/20 0.68
CYP2D6 P10635 1/20 0.68
NFKB1 P19838 1/20 0.68
HSD11B1 P28845 1/20 0.68
STAT3 P40763 1/20 0.68
NFKB2 Q00653 1/20 0.68
RELA Q04206 1/20 0.68
NFE2L2 Q16236 1/20 0.68
HPGD P15428 1/20 0.67
BCHE P06276 2/20 0.67
MAOA P21397 1/20 0.67
MAOB P27338 1/20 0.67

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30887530 1.00 TRPV1 (1.00) TRPV1KDM4EALDH1A1KMT2AACHE
SCHEMBL9029039 1.00 TRPV1 (1.00) TRPV1KDM4EALDH1A1KMT2AACHE
SCHEMBL17327997 0.99 TRPV1 (0.97) TRPV1KDM4EALDH1A1KMT2AACHE
SCHEMBL2123701 0.93 TRPV1 (0.87) TRPV1KDM4EALDH1A1KMT2AACHE
SCHEMBL5029885 0.93 TRPV1 (0.87) TRPV1KDM4EALDH1A1KMT2AACHE
SCHEMBL2123698 0.93 TRPV1 (0.87) TRPV1KDM4EALDH1A1KMT2AACHE
SCHEMBL29477290 0.91 TRPV1 (0.84) TRPV1KDM4EALDH1A1KMT2AACHE
SCHEMBL4912827 0.91 TRPV1 (0.84) TRPV1KDM4EALDH1A1KMT2AACHE
SCHEMBL3121297 0.89 KDM4E (0.97) TRPV1KDM4EALDH1A1KMT2AACHE
SCHEMBL3121290 0.89 KDM4E (0.97) TRPV1KDM4EALDH1A1KMT2AACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 138 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4599064-A1 AN RNA APTAMER THAT BINDS TO ASP7967 OR AN ANALOGUE THEREOF Okinawa Institute of Science and Technology School Corporation (JP) 2025-08-13 EP claimed
CN-119998451-A RNA aptamer binding to ASP7967 or analog thereof 学校法人冲绳科学技术大学院大学学园 2025-05-13 CN claimed
US-12116400-B2 Albumin variants and conjugates SARTORIUS ALBUMEDIX LIMITED (GB) 2024-10-15 US claimed
WO-2024075841-A1 AN RNA APTAMER THAT BINDS TO ASP7967 OR AN ANALOGUE THEREOF OKINAWA INSTITUTE OF SCIENCE AND TECHNOLOGY SCHOOL CORPORATION (JP) 2024-04-11 WO claimed
EP-3243835-B1 ALBUMIN VARIANTS AND CONJUGATES ALBUMEDIX LTD (GB) 2024-04-10 EP claimed
CN-117739978-A Multi-AUV parallel collaborative navigation positioning method and system based on factor graph 无锡学院 2024-03-22 CN claimed
EP-3337816-B1 ALBUMIN VARIANTS AND CONJUGATES ALBUMEDIX LTD (GB) 2024-02-14 EP claimed
US-20230039076-A1 ALBUMIN VARIANTS AND CONJUGATES SARTORIUS ALBUMEDIX LIMITED (GB) 2023-02-09 US claimed
EP-3569671-B1 METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME TAKASAGO PERFUMERY CO LTD (JP) 2022-06-22 EP claimed
US-11344488-B2 Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative TAKASAGO INTERNATIONAL CORPORATION (JP) 2022-05-31 US claimed
CN-110168038-B Methyl menthol derivative and cold sensate composition containing same 高砂香料工业株式会社 2022-05-27 CN claimed
CN-110837854-B AUV multi-source information fusion method and device based on factor graph 东南大学 2022-02-11 CN claimed
US-11236042-B2 Methylmenthol derivative and cool-sensation imparter composition containing same TAKASAGO INTERNATIONAL CORPORATION (JP) 2022-02-01 US claimed
US-20200297607-A1 COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE TAKASAGO INTERNATIONAL CORPORATION (JP) 2020-09-24 US claimed
EP-3699250-A1 COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE Takasago International Corporation (JP) 2020-08-26 EP claimed
US-10494330-B2 Methyl menthol derivative and cooling agent composition containing same TAKASAGO INTERNATIONAL CORPORATION (JP) 2019-12-03 US claimed
EP-3569671-A1 METHYLMENTHOL DERIVATIVE AND COOL-SENSATION IMPARTER COMPOSITION CONTAINING SAME Takasago International Corporation (JP) 2019-11-20 EP claimed
EP-3275962-B1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME TAKASAGO PERFUMERY CO LTD (JP) 2019-10-02 EP claimed
US-20180057447-A1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME TAKASAGO INTERNATIONAL CORPORATION (JP) 2018-03-01 US claimed
EP-3275962-A1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME Takasago International Corporation (JP) 2018-01-31 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200297607-A1 COOL-SENSATION IMPARTER COMPOSITION CONTAINING 2,2,6-TRIMETHYLCYCLOHEXANECARBOXYLIC ACID DERIVATIVE CNR2, ADRB2, TRPA1 TRPV1 5/4885KDM4E 4669/4885ALDH1A1 2031/4885
US-11344488-B2 Cool-sensation imparter composition containing 2,2,6-trimethylcyclohexanecarboxylic acid derivative CNR2, ADRB2, TRPA1 TRPV1 5/4885KDM4E 4669/4885ALDH1A1 2031/4885
US-20180057447-A1 METHYL MENTHOL DERIVATIVE AND COOLING AGENT COMPOSITION CONTAINING SAME TRPM4, TAS2R41, TRPM2 TRPV1 33/4885KDM4E 590/4885ALDH1A1 902/4885
US-10494330-B2 Methyl menthol derivative and cooling agent composition containing same TRPM4, TAS2R41, TRPM2 TRPV1 33/4885KDM4E 590/4885ALDH1A1 902/4885
US-11236042-B2 Methylmenthol derivative and cool-sensation imparter composition containing same TRPM8, TRPM4, TRPM2 TRPV1 6/4885KDM4E 2712/4885ALDH1A1 1703/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.