Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21408469 | 0.77 | ALDH1A1 (0.48) | BAZ2BBAZ2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL16416929 | 0.73 | KMT2A (0.43) | BAZ2BBAZ2ATDP1MAPTALDH1A1 | |
| SCHEMBL21266562 | 0.73 | RAB9A (0.46) | BAZ2BBAZ2AKDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL1277680 | 0.71 | KMT2A (0.53) | TDP1KDM4EGPR35SMN1; SMN2AR | |
| SCHEMBL9030971 | 0.71 | BAZ2B (0.43) | BAZ2BBAZ2AKDM4EMAPTALDH1A1 | |
| SCHEMBL16595640 | 0.71 | RXFP1 (0.53) | TDP1MAPTLMNAL3MBTL1 | |
| SCHEMBL1704844 | 0.70 | ABCB1 (0.47) | ABCB1TDP1MAPTALDH1A1GPR35 | |
| SCHEMBL1277233 | 0.70 | CYP1A2 (0.56) | KDM4ENPSR1MAPTGAAL3MBTL1 | |
| SCHEMBL10919254 | 0.70 | NPC1 (0.47) | KDM4EMAPTALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL9030367 | 0.70 | BAZ2B (0.42) | BAZ2BBAZ2ATDP1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714895-A1 | Pyrrole derivatives | F. Hoffmann-La Roche AG (CH) | 1996-06-05 | — | — | EP | disclosed |