Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.43 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.43 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6949726 | 0.87 | SMN1; SMN2 (0.41) | BAZ2BBAZ2AKAT2BKDM4EMAPT | |
| SCHEMBL10812847 | 0.79 | ALDH1A1 (0.38) | BAZ2BBAZ2AKAT2BKDM4EMAPT | |
| SCHEMBL11878553 | 0.76 | SMN1; SMN2 (0.46) | KDM4ESMN1; SMN2ALDH1A1RAB9ALMNA | |
| SCHEMBL7675730 | 0.76 | PPARA (0.40) | SMN1; SMN2ALDH1A1RAB9ANPC1HPGD | |
| SCHEMBL10990674 | 0.71 | HSP90AB1 (0.42) | KAT2BKDM4EMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL9029575 | 0.71 | BAZ2B (0.43) | BAZ2BBAZ2AKAT2BKDM4EMAPT | |
| SCHEMBL6367851 | 0.70 | MAPT (0.51) | KDM4EMAPTSMN1; SMN2RAB9ALMNA | |
| SCHEMBL7676895 | 0.70 | RAB9A (0.48) | KDM4EMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL6372557 | 0.70 | MAPT (0.48) | KDM4EMAPTSMN1; SMN2ALDH1A1RAB9A | |
| SCHEMBL19915720 | 0.70 | TBXAS1 (0.48) | KDM4EMAPTSMN1; SMN2RAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714895-A1 | Pyrrole derivatives | F. Hoffmann-La Roche AG (CH) | 1996-06-05 | — | — | EP | disclosed |