Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.42 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | LPO | P22079 | 2/20 | 0.34 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10817236 | 0.79 | ALDH1A1 (0.38) | BAZ2BBAZ2ALMNAL3MBTL1KDM4E | |
| SCHEMBL9030971 | 0.70 | BAZ2B (0.43) | BAZ2BBAZ2ALMNAL3MBTL1KDM4E | |
| SCHEMBL9029575 | 0.70 | BAZ2B (0.43) | BAZ2BBAZ2ALMNAL3MBTL1NPSR1 | |
| SCHEMBL2798571 | 0.68 | CA12 (0.48) | LMNAL3MBTL1NPSR1MAPTTDP1 | |
| SCHEMBL28825411 | 0.67 | MAPT (0.44) | NPSR1MAPTCASP1MEN1KMT2A | |
| SCHEMBL25409627 | 0.66 | CYP3A4 (0.42) | LMNAL3MBTL1HPGDSMN1; SMN2CASP1 | |
| SCHEMBL11104138 | 0.66 | KMT2A (0.49) | LMNAL3MBTL1NPSR1MAPK1KDM4E | |
| SCHEMBL16797527 | 0.66 | KMT2A (0.46) | LMNAL3MBTL1MAPK1KDM4EMAPT | |
| SCHEMBL23214661 | 0.65 | CASP1 (0.42) | LMNAKDM4EHPGDSMN1; SMN2CASP1 | |
| SCHEMBL11831054 | 0.65 | MAPT (0.51) | LMNAMAPTTDP1SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0714895-A1 | Pyrrole derivatives | F. Hoffmann-La Roche AG (CH) | 1996-06-05 | — | — | EP | disclosed |