Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMPRSS6 | Q8IU80 | 6/20 | 0.53 |
| ▸ | F2 | P00734 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.51 |
| ▸ | HPN | P05981 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12348116 | 0.91 | TMPRSS6 (0.57) | TMPRSS6F2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14599528 | 0.89 | ALDH1A1 (0.57) | TMPRSS6F2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14599613 | 0.89 | ALDH1A1 (0.57) | TMPRSS6F2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL14599610 | 0.89 | ALDH1A1 (0.57) | TMPRSS6F2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL5541901 | 0.89 | ALDH1A1 (0.57) | TMPRSS6F2LMNASMN1; SMN2ALDH1A1 | |
| SCHEMBL12348122 | 0.87 | TMPRSS6 (0.58) | TMPRSS6F2CA12CA1CA2 | |
| Hydrochloric Acid SCHEMBL27601325 | 0.83 | TMPRSS6 (0.56) | TMPRSS6F2LMNACA12CA1 | |
| SCHEMBL13956882 | 0.81 | CA1 (0.57) | LMNAHTTSMN1; SMN2CA12CA1 | |
| SCHEMBL14599604 | 0.80 | ALDH1A1 (0.59) | TMPRSS6F2LMNAHTTSMN1; SMN2 | |
| SCHEMBL8409042 | 0.79 | LMNA (0.60) | TMPRSS6F2LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |