Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 2/20 | 0.34 |
| ▸ | CASP1 | P29466 | 2/20 | 0.34 |
| ▸ | PRMT1 | Q99873 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TOP1 | P11387 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | ASIC3 | Q9UHC3 | 1/20 | 0.34 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.33 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.33 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.33 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.33 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169108 | 0.80 | LMNA (0.48) | CASP1PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL8169720 | 0.80 | C1S (0.44) | CASP1PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL8174039 | 0.80 | NQO2 (0.43) | CASP1PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL8170510 | 0.80 | NQO2 (0.44) | CASP1PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL9739115 | 0.77 | MMP3 (0.42) | MMP3ALDH1A1KIF11 | |
| SCHEMBL8176603 | 0.76 | NQO2 (0.48) | IDO1CASP1PRMT1ALDH1A1TOP1 | |
| SCHEMBL8176121 | 0.76 | HTT (0.39) | CASP1PRMT1ALDH1A1TOP1HPGD | |
| SCHEMBL8163067 | 0.76 | PRSS1 (0.54) | IDO1NQO2PARP10PARP2PRSS1 | |
| SCHEMBL9219029 | 0.76 | MMP3 (0.52) | MMP3ALDH1A1KIF11 | |
| SCHEMBL8169371 | 0.74 | PLAU (0.38) | NQO2PRSS1PRSS2PRSS3PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |