Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
| ▸ | KIF11 | P52732 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | CA2 | P00918 | 2/20 | 0.37 |
| ▸ | CA9 | Q16790 | 2/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.37 |
| ▸ | CA6 | P23280 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | TNKS | O95271 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9634014 | 0.87 | MMP3 (0.52) | MMP3CA12CA2CA9CA3 | |
| SCHEMBL1978737 | 0.87 | APP (0.41) | MMP3CA12CA2CA9ALDH1A1 | |
| SCHEMBL15818998 | 0.87 | MAOA (0.39) | ALDH1A1MAOAMAOBNOTUMTSHR | |
| SCHEMBL7194431 | 0.87 | ALDH1A1 (0.47) | KIF11CYP2A6ALDH1A1MAOAMAOB | |
| SCHEMBL7526479 | 0.86 | TSHR (0.43) | ALDH1A1MAOAMAOBTSHRGABRA1 | |
| SCHEMBL9219029 | 0.83 | MMP3 (0.52) | MMP3KIF11CA12CA2CA9 | |
| SCHEMBL15821103 | 0.83 | KIF11 (0.40) | MMP3KIF11CA12CA2CA9 | |
| SCHEMBL8532130 | 0.83 | CYP2A6 (0.47) | MMP3KIF11CYP2A6ALDH1A1LOXL2 | |
| SCHEMBL15819790 | 0.83 | KIF11 (0.39) | MMP3KIF11MAOAMAOBCYP11B2 | |
| SCHEMBL8530661 | 0.83 | THRB (0.41) | ALDH1A1MAOAMAOBTSHRPGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2780326-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | Vivolux Ab (SE) | 2014-09-24 | — | — | EP | disclosed |
| WO-2014100833-A1 | BENZAMIDE COMPOUNDS AND RELATED METHODS OF USE | NORTHWESTERN UNIVERSITY (US) | 2014-06-26 | — | — | WO | disclosed |
| WO-2013058691-A1 | METHOD FOR INHIBITION OF DEUBIQUITINATING ACTIVITY | VIVOLUX AB (SE) | 2013-04-25 | — | — | WO | disclosed |
| CN-101768042-A | Method for preparing polysubstituted indene skeleton derivative | UNIV FUDAN | 2010-07-07 | — | — | CN | disclosed |
| US-5134150-A | Administering diaryl-substituted imidazothiazoles; antiarthritic agents | SMITHKLINE BEECHAM CORPORATION (US) | 1992-07-28 | — | — | US | disclosed |