Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.36 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4229201 | 0.83 | GPR84 (0.47) | — | |
| SCHEMBL13924959 | 0.83 | GPR84 (0.47) | — | |
| SCHEMBL5326687 | 0.83 | GPR84 (0.47) | — | |
| SCHEMBL9029322 | 0.81 | FOLH1 (0.50) | L3MBTL1TSHRALDH1A1LMNAPPARG | |
| SCHEMBL1903133 | 0.79 | CA2 (0.42) | L3MBTL1SLC1A1 | |
| SCHEMBL11801523 | 0.79 | POLB (0.43) | TSHR | |
| SCHEMBL1533394 | 0.76 | CYP3A4 (0.37) | — | |
| SCHEMBL4254005 | 0.76 | TSHR (0.47) | L3MBTL1TSHRALDH1A1LMNAENPP2 | |
| SCHEMBL194844 | 0.76 | POLB (0.42) | TSHR | |
| SCHEMBL30045058 | 0.74 | POLB (0.35) | TSHRALDH1A1LMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0699203-A1 | THIOMARINOL DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES AND HERBICIDES | SMITHKLINE BEECHAM PLC (GB) | 1996-03-06 | — | — | EP | disclosed |
| WO-1994028001-A1 | THIOMARINOL DERIVATIVES, PROCESS AND INTERMEDIATES FOR THEIR PREPARATION AND THEIR USE AS MICROBICIDES AND HERBICIDES | SMITHKLINE BEECHAM PLC (GB) | 1994-12-08 | — | — | WO | disclosed |