Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12021938 | 0.77 | SMN1; SMN2 (0.34) | LMNARECQLKMT2AGAAMEN1 | |
| SCHEMBL903036 | 0.72 | LMNA (0.34) | LMNARECQLKMT2AGAAMEN1 | |
| SCHEMBL23062876 | 0.71 | BRD4 (0.40) | LMNARECQLKMT2AGAAMEN1 | |
| SCHEMBL903112 | 0.70 | TSHR (0.32) | KMT2AMEN1ALDH1A1 | |
| SCHEMBL903082 | 0.69 | ALDH1A1 (0.33) | LMNARECQLKMT2AGAAMEN1 | |
| SCHEMBL21590983 | 0.69 | LMNA (0.32) | LMNARECQL | |
| SCHEMBL903056 | 0.66 | — | — | |
| SCHEMBL6889091 | 0.66 | RECQL (0.43) | LMNARECQLKMT2AGAAMEN1 | |
| SCHEMBL10082089 | 0.65 | KDM4E (0.31) | KDM4E | |
| SCHEMBL10279301 | 0.65 | LMNA (0.39) | LMNARECQLKMT2AGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044531-A1 | NOVEL PIPERAZINE ANALOGS WITH SUBSTITUTED HETEROARYL GROUPS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-04-05 | — | — | WO | disclosed |