Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX1 | Q96LB2 | 1/20 | 0.57 |
| ▸ | F2 | P00734 | 5/20 | 0.56 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.56 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.56 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.56 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.56 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.56 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.52 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.51 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.51 |
| ▸ | NR4A3 | Q92570 | 1/20 | 0.51 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.51 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8681578 | 0.83 | ALDH1A1 (0.61) | TP53MAPTPLA2G4BNR4A1NR4A2 | |
| SCHEMBL2008979 | 0.83 | MAPK1 (0.56) | PARP10TP53MAPTPLA2G4BNR4A1 | |
| SCHEMBL8479686 | 0.82 | RAB9A (0.62) | PARP10TP53MAPTPLA2G4BNR4A1 | |
| SCHEMBL8011529 | 0.82 | LMNA (0.62) | TP53MAPTPLA2G4BNR4A1NR4A2 | |
| SCHEMBL8013977 | 0.82 | ALOX15 (0.61) | TP53MAPTPLA2G4BNR4A1NR4A2 | |
| Hydrochloric Acid SCHEMBL27505257 | 0.82 | ALDH1A1 (0.59) | TP53MAPTPLA2G4BNR4A1NR4A2 | |
| SCHEMBL6629683 | 0.82 | F2 (0.83) | MRGPRX1F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5288304 | 0.81 | MAPT (0.59) | TP53MAPTPLA2G4BKDM4ELMNA | |
| SCHEMBL2006466 | 0.81 | MAPK1 (0.56) | PARP10TP53MAPTPLA2G4BNR4A1 | |
| Hydrochloric Acid SCHEMBL23541015 | 0.81 | F2 (0.83) | MRGPRX1F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |