Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.59 |
| ▸ | F7 | P08709 | 4/20 | 0.59 |
| ▸ | F3 | P13726 | 4/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.59 |
| ▸ | PPARG | P37231 | 3/20 | 0.59 |
| ▸ | PPARD | Q03181 | 3/20 | 0.59 |
| ▸ | PPARA | Q07869 | 3/20 | 0.59 |
| ▸ | FABP3 | P05413 | 3/20 | 0.59 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.59 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.59 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.59 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.59 |
| ▸ | FABP4 | P15090 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | GNA15 | P30679 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3487349 | 0.92 | ALDH1A1 (0.56) | ALDH1A1F7F3KDM4EPPARG | |
| SCHEMBL3487344 | 0.92 | ALDH1A1 (0.56) | ALDH1A1F7F3KDM4EPPARG | |
| SCHEMBL9196814 | 0.87 | FAAH (0.66) | F7F3PPARGPPARDPPARA | |
| SCHEMBL17237707 | 0.87 | EPHX2 (0.59) | F7F3PPARGPPARDPPARA | |
| SCHEMBL17237703 | 0.87 | EPHX2 (0.59) | F7F3PPARGPPARDPPARA | |
| SCHEMBL8567370 | 0.85 | CES2 (0.64) | ALDH1A1PPARGPPARDPPARAFFAR1 | |
| SCHEMBL11242983 | 0.85 | CES2 (0.64) | ALDH1A1PPARGPPARDPPARAFFAR1 | |
| SCHEMBL15295117 | 0.85 | PPARG (0.70) | ALDH1A1F7F3KDM4EPPARG | |
| SCHEMBL6293226 | 0.84 | EPHX2 (0.69) | ALDH1A1F7F3KDM4EPPARG | |
| SCHEMBL6923085 | 0.84 | EPHX2 (0.69) | ALDH1A1F7F3KDM4EPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9725720-B2 | Low molecular weight cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-9725720-B2 | Low molecular weight cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2017-08-08 | — | — | US | disclosed |
| US-20170015998-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | SIRNA THERAPEUTICS, INC. (US) | 2017-01-19 | — | — | US | disclosed |
| US-20170015998-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | SIRNA THERAPEUTICS, INC. (US) | 2017-01-19 | — | — | US | disclosed |
| US-9458087-B2 | Low molecular weight cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-9458087-B2 | Low molecular weight cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-20150284316-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | BANK OF AMERICA, N.A. | 2015-10-08 | — | — | US | disclosed |
| US-20150284316-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | BANK OF AMERICA, N.A. | 2015-10-08 | — | — | US | disclosed |
| US-9029604-B2 | Low molecular weight cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-9029604-B2 | Low molecular weight cationic lipids for oligonucleotide delivery | SIRNA THERAPEUTICS, INC. (US) | 2015-05-12 | — | — | US | disclosed |
| US-20130274523-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | BANK OF AMERICA, N.A. | 2013-10-17 | — | — | US | disclosed |
| US-20130274523-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | BANK OF AMERICA, N.A. | 2013-10-17 | — | — | US | disclosed |
| WO-2012044638-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | MERCK SHARP & DOHME CORP. (US) | 2012-04-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130274523-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | LDLR, APOB, CETP | ALDH1A1 4090/4885F7 2163/4885F3 1540/4885 |
| US-20170015998-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | LDLR, APOB, CETP | ALDH1A1 4090/4885F7 2163/4885F3 1540/4885 |
| US-20150284316-A1 | LOW MOLECULAR WEIGHT CATIONIC LIPIDS FOR OLIGONUCLEOTIDE DELIVERY | LDLR, APOB, CETP | ALDH1A1 4090/4885F7 2163/4885F3 1540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.