Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 known ✓ | P31645 | 8/20 | 0.51 |
| ▸ | HTR1A | P08908 | 7/20 | 0.51 |
| ▸ | DRD2 | P14416 | 4/20 | 0.50 |
| ▸ | HTR7 | P34969 | 4/20 | 0.50 |
| ▸ | HTR6 | P50406 | 4/20 | 0.50 |
| ▸ | HTR2A | P28223 | 3/20 | 0.50 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.48 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.48 |
| ▸ | KDM4A | O75164 | 1/20 | 0.47 |
| ▸ | KDM4B | O94953 | 1/20 | 0.47 |
| ▸ | KDM5C | P41229 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455861 | 0.96 | SLC6A4 (0.53) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Oxalic Acid SCHEMBL9048417 | 0.90 | SLC6A4 (0.55) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Oxalic Acid SCHEMBL9046848 | 0.88 | HTR1A (0.51) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Oxalic Acid SCHEMBL9046888 | 0.88 | CCR2 (0.44) | HTR1ADRD2KDM4AKDM4BKDM5C | |
| Oxalic Acid SCHEMBL9048518 | 0.88 | OPRM1 (0.58) | DRD2HTR6KDM4AKDM4BKDM5C | |
| Oxalic Acid SCHEMBL9046836 | 0.86 | SLC6A4 (0.51) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Maleic Acid SCHEMBL9046255 | 0.85 | KDM4A (0.49) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| Maleic Acid SCHEMBL30909027 | 0.85 | KDM4A (0.49) | SLC6A4HTR1ADRD2HTR7HTR6 | |
| SCHEMBL7460711 | 0.85 | CYP1A2 (0.53) | DRD2HTR7KDM4AKDM4BKDM5C | |
| Oxalic Acid SCHEMBL9030775 | 0.85 | SLC6A4 (0.60) | SLC6A4HTR1ADRD2HTR7HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0708102-A1 | 5-HT1F agonists for the treatment of migraine | ELI LILLY AND COMPANY (US) | 1996-04-24 | — | — | EP | disclosed |