Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRSS1 | P07477 | 3/20 | 0.44 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.44 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.38 |
| ▸ | HTR3B | O95264 | 2/20 | 0.38 |
| ▸ | HTR3A | P46098 | 2/20 | 0.38 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.38 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.38 |
| ▸ | C1S | P09871 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | F7 | P08709 | 1/20 | 0.36 |
| ▸ | F3 | P13726 | 1/20 | 0.36 |
| ▸ | WDR5 | P61964 | 1/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169108 | 0.83 | LMNA (0.48) | PRSS1PRSS2PRSS3C1SLMNA | |
| SCHEMBL8162971 | 0.82 | C1S (0.57) | PRSS1PRSS2PRSS3C1SPARP1 | |
| SCHEMBL8169397 | 0.82 | PRSS1 (0.44) | PRSS1PRSS2PRSS3C1SPARP1 | |
| SCHEMBL3022644 | 0.78 | ALOX5 (0.42) | ALOX5IDO1TAAR1 | |
| SCHEMBL8556617 | 0.75 | F10 (0.37) | PRSS1PRSS2PRSS3C1SF2 | |
| SCHEMBL2202463 | 0.74 | PARP1 (0.63) | PRSS1PRSS2PRSS3HTR3EHTR3B | |
| SCHEMBL8162967 | 0.74 | PRSS1 (0.39) | PRSS1PRSS2PRSS3C1SF2 | |
| SCHEMBL8169720 | 0.73 | C1S (0.44) | PRSS1PRSS2PRSS3C1SF2 | |
| SCHEMBL8170510 | 0.73 | NQO2 (0.44) | PRSS1PRSS2PRSS3C1SF2 | |
| SCHEMBL8174039 | 0.73 | NQO2 (0.43) | PRSS1PRSS2PRSS3C1SF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0730590-A1 | NOVEL ISOXAZOLINE AND ISOXAZOLE FIBRINOGEN RECEPTOR ANTAGONISTS | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1996-09-11 | — | — | EP | disclosed |