Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.33 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | PTGES | O14684 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9881658 | 0.81 | KMT2A (0.46) | NPSR1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL1930001 | 0.80 | ALDH1A1 (0.48) | NPSR1ALDH1A1HTTGAAMEN1 | |
| SCHEMBL31667226 | 0.78 | ALDH1A1 (0.40) | NPSR1L3MBTL1KDM4EALDH1A1HTT | |
| SCHEMBL903087 | 0.77 | NPC1 (0.38) | L3MBTL1KDM4EALDH1A1HTTNPC1 | |
| SCHEMBL729060 | 0.76 | L3MBTL1 (0.46) | NPSR1L3MBTL1KDM4EALDH1A1HTT | |
| SCHEMBL1412412 | 0.76 | NPC1 (0.47) | NPSR1KDM4EALDH1A1NPC1GAA | |
| SCHEMBL16442926 | 0.75 | MEN1 (0.41) | L3MBTL1KDM4EALDH1A1GAAMEN1 | |
| SCHEMBL9194890 | 0.74 | KDM4E (0.42) | NPSR1L3MBTL1KDM4EALDH1A1POLB | |
| SCHEMBL25759724 | 0.74 | SMN1; SMN2 (0.50) | NPSR1L3MBTL1KDM4EALDH1A1NPC1 | |
| SCHEMBL1930172 | 0.73 | NPSR1 (0.43) | NPSR1KDM4EALDH1A1HTTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012044531-A1 | NOVEL PIPERAZINE ANALOGS WITH SUBSTITUTED HETEROARYL GROUPS AS BROAD-SPECTRUM INFLUENZA ANTIVIRALS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-04-05 | — | — | WO | disclosed |
| US-20090209430-A1 | TEMPLATE DIRECTED SPLIT AND MIX SYSTHESIS OF SMALL MOLECULE LIBRARIES | NUEVOLUTION A/S (DK) | 2009-08-20 | — | — | US | disclosed |