Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 14/20 | 0.75 |
| ▸ | PDE4B | Q07343 | 14/20 | 0.75 |
| ▸ | PDE4C | Q08493 | 14/20 | 0.75 |
| ▸ | PDE4D | Q08499 | 14/20 | 0.75 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.75 |
| ▸ | ADORA2B | P29275 | 10/20 | 0.62 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.62 |
| ▸ | HPGD | P15428 | 1/20 | 0.62 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | BRD4 | O60885 | 1/20 | 0.47 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124420 | 0.92 | PDE4A (0.74) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7990332 | 0.86 | PDE4A (0.58) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL7602847 | 0.86 | PDE4A (1.00) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9069127 | 0.85 | ADORA2A (0.72) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL1460898 | 0.81 | PDE4A (0.75) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL9791629 | 0.81 | PDE4A (0.89) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL8005197 | 0.81 | ADORA2B (0.59) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL11072066 | 0.80 | PDE4A (0.70) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL11080222 | 0.79 | PDE4A (0.68) | PDE4APDE4BPDE4CPDE4DADORA2A | |
| SCHEMBL1376703 | 0.79 | ADORA2A (0.59) | PDE4APDE4BPDE4CPDE4DADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0417790-B1 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO KK (JP) | 1996-12-04 | — | — | EP | disclosed |
| US-5173492-A | Bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-12-22 | — | — | US | disclosed |
| EP-0191313-B1 | 6-THIOXANTHINE DERIVATIVES | Euro-Celtique S.A. (LU) | 1992-10-28 | — | — | EP | disclosed |
| CN-1013676-B | 6-THIOXANTHINE DERIVATIVES | EURO CELTIQUE SA (US) | 1991-08-28 | — | — | CN | disclosed |
| EP-0417790-A2 | S-triazolo[3,4-i]purine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1991-03-20 | — | — | EP | disclosed |
| US-4820709-A | 6-thioxanthine derivatives | EUROCELTIQUE, S.A. (LU) | 1989-04-11 | — | — | US | disclosed |
| US-4710503-A | 6-thioxanthine derivatives | EUROCELTIQUE S.A. (LU) | 1987-12-01 | — | — | US | disclosed |
| CN-86101050-A | The manufacture method of 6-Thioxanthine derivatives and application thereof | — | 1986-11-12 | — | — | CN | disclosed |
| EP-0191313-A1 | 6-Thioxanthine derivatives | Euro-Celtique S.A. (LU) | 1986-08-20 | — | — | EP | disclosed |