Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8097764 | 0.83 | HDAC4 (0.46) | SLC9A1SLC6A3HTR2CSLC6A2 | |
| SCHEMBL9031961 | 0.78 | ABCC1 (0.46) | HTR2A | |
| SCHEMBL11458171 | 0.74 | HDAC4 (0.44) | SLC9A1SLC6A3HTR2CSLC6A2 | |
| SCHEMBL805079 | 0.72 | SLC9A1 (0.60) | SLC9A1CNR1HTR2AHTR2CHTR2B | |
| SCHEMBL6832060 | 0.72 | SLC9A1 (0.60) | SLC9A1CNR1HTR2AHTR2CHTR2B | |
| SCHEMBL301295 | 0.72 | SLC9A1 (0.60) | SLC9A1CNR1HTR2AHTR2CHTR2B | |
| SCHEMBL13544388 | 0.72 | SLC9A1 (0.60) | SLC9A1CNR1HTR2AHTR2CHTR2B | |
| SCHEMBL3751420 | 0.72 | SLC9A1 (0.60) | SLC9A1CNR1HTR2AHTR2CHTR2B | |
| SCHEMBL7651885 | 0.72 | SLC9A1 (0.60) | SLC9A1CNR1HTR2AHTR2CHTR2B | |
| SCHEMBL4210867 | 0.72 | SLC9A1 (0.60) | SLC9A1CNR1HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0487095-B1 | Pyridyl derivatives, medicines containing these compounds and processes for their preparation | THOMAE GMBH DR K (DE) | 1996-02-28 | — | — | EP | disclosed |
| EP-0487095-A1 | Pyridyl derivatives, medicines containing these compounds and processes for their preparation | Dr. Karl Thomae GmbH (DE) | 1992-05-27 | — | — | EP | disclosed |