Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.32 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.32 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033022 | 0.87 | POLB (0.37) | SLC6A3SLC6A2SLC6A4ALDH1A1NPSR1 | |
| SCHEMBL9034907 | 0.84 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4ALDH1A1NPSR1 | |
| SCHEMBL9033398 | 0.82 | SLC6A3 (0.42) | SLC6A3SLC6A2SLC6A4ALDH1A1POLB | |
| SCHEMBL8697840 | 0.81 | POLB (0.37) | SLC6A3SLC6A2SLC6A4ALDH1A1LMNA | |
| SCHEMBL9033059 | 0.79 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4HPGDRAB9A | |
| SCHEMBL9033194 | 0.79 | HRH3 (0.45) | ALDH1A1NPSR1LMNAMAPTHPGD | |
| SCHEMBL8697759 | 0.79 | HRH3 (0.45) | ALDH1A1NPSR1LMNAMAPTHPGD | |
| SCHEMBL9034654 | 0.78 | SLC6A2 (0.35) | SLC6A3SLC6A2SLC6A4ALDH1A1MAPT | |
| SCHEMBL9033707 | 0.75 | POLB (0.38) | SLC6A3SLC6A2SLC6A4ALDH1A1LMNA | |
| SCHEMBL9032746 | 0.71 | POLB (0.39) | ALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |