Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 3/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | CTSL | P07711 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034695 | 0.90 | CTSL (0.34) | CTSLALDH1A1MAPTKDM4EGAA | |
| SCHEMBL9034907 | 0.81 | SLC6A3 (0.40) | SLC6A2SLC6A3SLC6A4ALDH1A1GAA | |
| SCHEMBL9034647 | 0.78 | CTSL (0.38) | CTSLALDH1A1MAPTKDM4EGAA | |
| SCHEMBL9032190 | 0.78 | SLC6A3 (0.40) | SLC6A2SLC6A3SLC6A4ALDH1A1MAPT | |
| SCHEMBL9033059 | 0.76 | SLC6A3 (0.39) | SLC6A2SLC6A3SLC6A4TSHRCACNA1B | |
| SCHEMBL9032746 | 0.73 | POLB (0.39) | CTSLALDH1A1TSHRCYP1A2SMN1; SMN2 | |
| SCHEMBL9033707 | 0.72 | POLB (0.38) | SLC6A2SLC6A3SLC6A4ALDH1A1TSHR | |
| SCHEMBL9034593 | 0.69 | CYP3A4 (0.39) | CTSLTSHRCYP2C9CYP2C19SMN1; SMN2 | |
| SCHEMBL9033398 | 0.69 | SLC6A3 (0.42) | SLC6A2SLC6A3SLC6A4ALDH1A1CACNA1B | |
| SCHEMBL9033022 | 0.68 | POLB (0.37) | SLC6A2SLC6A3SLC6A4ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |