Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | MLNR | O43193 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | FYN | P06241 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034907 | 0.83 | SLC6A3 (0.40) | POLBCYP2D6SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8697840 | 0.78 | POLB (0.37) | POLBCYP2D6HRH3SLC6A2SLC6A4 | |
| SCHEMBL9032190 | 0.75 | SLC6A3 (0.40) | POLBSLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL9033022 | 0.75 | POLB (0.37) | POLBCYP2D6HRH3FDPSSLC6A2 | |
| SCHEMBL9033059 | 0.75 | SLC6A3 (0.39) | POLBCYP2D6FDPSSLC6A2SLC6A4 | |
| SCHEMBL9032746 | 0.73 | POLB (0.39) | POLBALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL9034654 | 0.72 | SLC6A2 (0.35) | SLC6A2SLC6A4SLC6A3MEN1ALDH1A1 | |
| SCHEMBL9034695 | 0.72 | CTSL (0.34) | POLBMEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL8697765 | 0.70 | HRH3 (0.43) | HRH3ALDH1A1 | |
| SCHEMBL13265145 | 0.68 | POLB (0.45) | POLBMEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |