Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | CACNB1 | Q02641 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032190 | 0.82 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4POLBCACNA2D1 | |
| SCHEMBL8700872 | 0.77 | HRH3 (0.47) | ALDH1A1 | |
| SCHEMBL9034907 | 0.75 | SLC6A3 (0.40) | SLC6A3SLC6A2SLC6A4POLBALDH1A1 | |
| SCHEMBL9033059 | 0.73 | SLC6A3 (0.39) | SLC6A3SLC6A2SLC6A4POLBCACNA2D1 | |
| SCHEMBL9033022 | 0.71 | POLB (0.37) | SLC6A3SLC6A2SLC6A4POLBCACNA2D1 | |
| SCHEMBL8697840 | 0.70 | POLB (0.37) | SLC6A3SLC6A2SLC6A4POLBCACNA2D1 | |
| SCHEMBL9034654 | 0.69 | SLC6A2 (0.35) | SLC6A3SLC6A2SLC6A4CACNA1BALDH1A1 | |
| SCHEMBL9032764 | 0.68 | POLB (0.35) | POLBCACNA2D1CACNA1BCACNB1 | |
| SCHEMBL9033048 | 0.68 | ALDH1A1 (0.46) | POLBALDH1A1 | |
| SCHEMBL22916606 | 0.67 | RAB9A (0.56) | SLC6A3SLC6A2SLC6A4POLBALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |