⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL755487 | 0.83 | KMT2A (0.39) | — | |
| SCHEMBL2525666 | 0.82 | CAMK2A (0.46) | — | |
| SCHEMBL2529981 | 0.80 | GPR84 (0.46) | — | |
| SCHEMBL2529890 | 0.78 | GPR84 (0.50) | — | |
| SCHEMBL25836002 | 0.78 | GPR84 (0.50) | — | |
| SCHEMBL28427000 | 0.78 | KDM4E (0.31) | — | |
| SCHEMBL2529977 | 0.78 | GPR84 (0.50) | — | |
| SCHEMBL16640759 | 0.78 | FAAH (0.46) | — | |
| SCHEMBL5021516 | 0.78 | FAAH (0.40) | — | |
| SCHEMBL13661862 | 0.75 | FAAH (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8461135-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2013-06-11 | — | — | US | claimed |
| US-8039450-B2 | Boron-containing small molecules as anti-inflammatory agents | ANACOR PHARMACEUTICALS, INC. (US) | 2011-10-18 | — | — | US | claimed |
| US-20030119785-A1 | Vitronectin receptor antagonists, their preparation and use | HOECHST AKTIENGESELLSCHAFT AND GENENTECH INC. | 2003-06-26 | — | — | US | claimed |
| US-20030027807-A1 | Vitronectin receptor antagonists, their preparation and their use | GENENTECH, INC. AND HOECHST AKTIENGESELLSCHAFT | 2003-02-06 | — | — | US | claimed |
| US-20010011087-A1 | Vitronectin receptor antagonists, their preparation and their use | WEHNER VOLKMAR (DE) | 2001-08-02 | — | — | US | claimed |
| US-6218387-B1 | AS INHIBITORS OF BONE RESORPTION BY OSTEOCLASTS, FOR INHIBITING TUMOR GROWTH OR TUMOR METASTASIS, INHIBITING INFLAMMATION, OR FOR TREATMENT OR PROPHYLAXIS OF CARDIOVASCULAR DISEASES, NEUROPATHIES OR RETINOPATHIES | HOECHST AKTIENGESELLSCHAFT (DE) | 2001-04-17 | — | — | US | claimed |
| US-6207663-B1 | AS INHIBITORS OF BONE RESORPTION, TUMOR GROWTH, TUMOR METASTASIS, OR INFLAMMATION, OR FOR THE TREATMENT OR PROPHYLAXIS OF CARDIOVASCULAR DISORDERS, NEPHROPATHIES OR RETINOPATHIES | HOECHST ATKIENGESELLSCHAFT (DE) | 2001-03-27 | — | — | US | claimed |
| EP-0854145-A2 | Vitronectin receptor antagonists, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-22 | — | — | EP | claimed |
| EP-0854140-A2 | Vitronectin receptor antagonists, their production and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1998-07-22 | — | — | EP | claimed |
| US-11718758-B2 | Aqueous dispersion of colored particles | MITSUBISHI PENCIL COMPANY, LIMITED (JP) | 2023-08-08 | — | — | US | disclosed |
| EP-3725854-B1 | COLORED PARTICLE AQUEOUS DISPERSION | MITSUBISHI PENCIL CO (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-20180170855-A1 | TREPROSTINIL DERIVATIVES AND COMPOSITIONS AND USES THEREOF | Corsair Pharma, Inc. | 2018-06-21 | — | — | US | disclosed |
| CN-107739341-A | A kind of preparation method of climbazole | 江苏绿叶农化有限公司 | 2018-02-27 | — | — | CN | disclosed |
| US-9873709-B2 | Triazolopyridine compounds, compositions and methods of use thereof | GENENTECH, INC. (US) | 2018-01-23 | — | — | US | disclosed |
| WO-1996003377-A1 | HETEROCYCLIC COMPOUNDS, USEFUL AS ALLOSTERIC EFFECTORS AT MUSCARINIC RECEPTORS | SANKYO COMPANY, LIMITED (JP) | 1996-02-08 | — | — | WO | disclosed |
| EP-0384189-A2 | Optically active compound and a process for the production thereof | CHISSO CORPORATION (JP) | 1990-08-29 | — | — | EP | disclosed |
| US-4914222-A | DISSOLVING ESTER IN NONPOLAR WATER-IMMISCIBLE SOLVENT, ADDING HYDROXYLATED SOLVENT AND OXYGENATED ACID, CRYSTALLIZING SALT | MERCK & CO., INC. (US) | 1990-04-03 | — | — | US | disclosed |
| EP-0347840-A2 | Phosphinic acid derivates | BANYU PHARMACEUTICAL CO., LTD. (JP) | 1989-12-27 | — | — | EP | disclosed |
| EP-0034536-B1 | OXIME DERIVATIVES OF 3-ALKYLOXY- OR 3-ALKYLTHIOMETHYL 7-AMINO-THIAZOLYLACETAMIDO CEPHALOSPORANIC ACID, THEIR PREPARATION, THEIR USE AS MEDICAMENTS AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1984-12-27 | — | — | EP | disclosed |
| US-4448776-A | Method of using certain substituted aliphatic secondary amines or their salts for easing breathing | BUCHER KARL (CH) | 1984-05-15 | — | — | US | disclosed |