Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033660 | 0.84 | STAT3 (0.39) | STAT3ACHETSHRFFAR1ALDH1A1 | |
| SCHEMBL8660435 | 0.82 | POLB (0.42) | FFAR1ALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL3822853 | 0.80 | CYP1A2 (0.48) | ALDH1A1SMN1; SMN2CYP1A2 | |
| SCHEMBL4623899 | 0.78 | ESR1 (0.46) | TSHRALDH1A1TDP1KDM4EMAPT | |
| SCHEMBL6935978 | 0.78 | STAT3 (0.46) | STAT3ACHEFFAR1ALDH1A1TDP1 | |
| SCHEMBL5321358 | 0.78 | BRD4 (0.50) | TSHRFFAR1LMNABRD4CYP1A2 | |
| SCHEMBL9034467 | 0.77 | FAAH (0.41) | TSHRALDH1A1ESR1ESR2LMNA | |
| SCHEMBL3700232 | 0.77 | LMNA (0.41) | FFAR1ALDH1A1NPSR1MAPTLMNA | |
| SCHEMBL9034681 | 0.76 | FAAH (0.42) | TSHRESR1ESR2LMNA | |
| SCHEMBL4729080 | 0.76 | ALDH1A1 (0.50) | TSHRALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0705245-A1 | NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1996-04-10 | — | — | EP | disclosed |
| WO-1995000480-A1 | NOVEL INTERMEDIATES FOR THE PREPARATION OF ANTIHISTAMINIC 4-DIPHENYLMETHYL/DIPHENYLMETHOXY PIPERIDINE DERIVATIVES | MERRELL PHARMACEUTICALS INC. (US) | 1995-01-05 | — | — | WO | disclosed |