Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 13/20 | 0.35 |
| ▸ | TERT | O14746 | 1/20 | 0.34 |
| ▸ | ARG1 | P05089 | 2/20 | 0.34 |
| ▸ | ARG2 | P78540 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 5/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.33 |
| ▸ | FAP | Q12884 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032688 | 0.83 | L3MBTL1 (0.33) | MMEACECPA1ACE2 | |
| SCHEMBL9033537 | 0.80 | L3MBTL1 (0.32) | — | |
| SCHEMBL9033793 | 0.79 | — | — | |
| SCHEMBL9034247 | 0.77 | DPP4 (0.38) | DPP4TERTARG1ARG2DPP8 | |
| SCHEMBL9033802 | 0.76 | ENPEP (0.33) | — | |
| SCHEMBL9032679 | 0.75 | L3MBTL1 (0.31) | MMEACECPA1ACE2 | |
| SCHEMBL9033533 | 0.74 | HPGD (0.31) | — | |
| SCHEMBL9033517 | 0.74 | POLB (0.40) | — | |
| SCHEMBL9032645 | 0.74 | MEN1 (0.38) | — | |
| SCHEMBL9050945 | 0.73 | MEN1 (0.36) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |