Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.47 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.47 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | SYK | P43405 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.42 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 6/20 | 0.42 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 4/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033039 | 0.91 | OPRK1 (0.51) | OPRK1ITGB3ITGA2BCTSLACE | |
| SCHEMBL9033091 | 0.83 | CTSL (0.46) | OPRK1ITGB3ITGA2BCTSLSYK | |
| SCHEMBL9033818 | 0.82 | CTSL (0.45) | OPRK1ITGB3ITGA2BCTSLSYK | |
| SCHEMBL5561950 | 0.81 | SYK (0.49) | CTSLSYKP2RX7CTSK | |
| SCHEMBL5566516 | 0.79 | SYK (0.45) | ITGB3ITGA2BCTSLSYKCTSK | |
| SCHEMBL5566427 | 0.79 | SYK (0.45) | ITGB3ITGA2BCTSLSYKCTSK | |
| SCHEMBL19485480 | 0.78 | CTSK (0.62) | ITGB3ITGA2BCTSLSYKCTSK | |
| SCHEMBL9219338 | 0.78 | CTSK (0.62) | ITGB3ITGA2BCTSLSYKCTSK | |
| SCHEMBL6781311 | 0.77 | CTSK (0.58) | CTSLSYKCTSK | |
| SCHEMBL9034005 | 0.77 | CTSL (0.43) | OPRK1ITGB3ITGA2BCTSLSYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |