Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | SYK | P43405 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033091 | 0.99 | CTSL (0.46) | CTSLCTSBCTSKSYKOPRK1 | |
| SCHEMBL9032737 | 0.89 | CTSL (0.44) | CTSLCTSBCTSKOPRK1ITGB3 | |
| SCHEMBL9031818 | 0.88 | CTSL (0.44) | CTSLCTSBCTSKOPRK1ITGB3 | |
| SCHEMBL9034005 | 0.86 | CTSL (0.43) | CTSLCTSBCTSKSYKOPRK1 | |
| SCHEMBL9033382 | 0.85 | CTSL (0.43) | CTSLCTSBCTSKSYKOPRK1 | |
| SCHEMBL9034272 | 0.84 | ATM (0.45) | CTSLCTSBCTSKOPRK1ITGB3 | |
| SCHEMBL8697846 | 0.83 | OPRK1 (0.44) | CTSLCTSBCTSKOPRK1ITGB3 | |
| SCHEMBL8698405 | 0.82 | HRH3 (0.39) | CTSLCTSBCTSKMAPTSMN1; SMN2 | |
| SCHEMBL9034307 | 0.82 | OPRK1 (0.48) | CTSLCTSKSYKOPRK1ITGB3 | |
| SCHEMBL9034647 | 0.81 | CTSL (0.38) | CTSLCTSBCTSKMAPTADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |