Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 3/20 | 0.52 |
| ▸ | CA2 | P00918 | 3/20 | 0.52 |
| ▸ | CA7 | P43166 | 2/20 | 0.52 |
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA4 | P22748 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033969 | 0.80 | NPSR1 (0.39) | ALDH1A1SMN1; SMN2TSHRNPSR1KMT2A | |
| SCHEMBL9161422 | 0.78 | KMT2A (0.38) | ALDH1A1L3MBTL1GAASMN1; SMN2TDP1 | |
| SCHEMBL8799400 | 0.77 | MAOB (0.39) | ADRA2BKMT2ANFE2L2 | |
| SCHEMBL2737143 | 0.76 | CA1 (0.65) | CA1CA2CA7CA9CA12 | |
| SCHEMBL3417543 | 0.76 | ERN1 (0.43) | CA1CA2CA7CA9CA12 | |
| SCHEMBL28460446 | 0.76 | ADRB2 (0.41) | ALDH1A1HTTMAPK1L3MBTL1SMN1; SMN2 | |
| SCHEMBL9037118 | 0.76 | POLB (0.37) | ALDH1A1L3MBTL1GAAPOLBSMN1; SMN2 | |
| SCHEMBL9034506 | 0.76 | ADRA2A (0.38) | GAASMN1; SMN2HTR6ADRA2BKMT2A | |
| 1,2-Dimethoxybenzene SCHEMBL27829075 | 0.75 | CA1 (0.72) | CA1CA2CA7CA9CA12 | |
| 1,2-Dimethoxybenzene SCHEMBL28252141 | 0.73 | CA1 (0.68) | CA1CA2CA7CA9CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396698-A1 | MANUFACTURE OF ARYLOXYALDEHYDES. | ICI PLC (GB) | 1990-11-14 | — | — | EP | claimed |
| WO-1990004580-A1 | ARYLOXYALDEHYDES AND THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-03 | — | — | WO | claimed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| EP-0396698-B1 | MANUFACTURE OF ARYLOXYALDEHYDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-23 | — | — | EP | disclosed |
| US-5169974-A | Process for manufacturing aryloxyaldehydes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-08 | — | — | US | disclosed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0396698-A1 | MANUFACTURE OF ARYLOXYALDEHYDES. | ICI PLC (GB) | 1990-11-14 | — | — | EP | disclosed |
| WO-1990004580-A1 | ARYLOXYALDEHYDES AND THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-03 | — | — | WO | disclosed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | disclosed |