Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.43 |
| ▸ | TLR2 | O60603 | 1/20 | 0.43 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.43 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5008996 | 0.76 | ALDH1A1 (0.44) | ERN1TLR2TLR1TLR6KDM4E | |
| SCHEMBL9034308 | 0.76 | CA1 (0.52) | ERN1TLR2TLR1TLR6ALDH1A1 | |
| SCHEMBL9033969 | 0.76 | NPSR1 (0.39) | KDM4EALDH1A1HPGDNPC1SMN1; SMN2 | |
| SCHEMBL9161422 | 0.74 | KMT2A (0.38) | ALDH1A1LMNAMAPTCYP3A4HPGD | |
| SCHEMBL8799400 | 0.73 | MAOB (0.39) | HSD11B1 | |
| SCHEMBL9034506 | 0.72 | ADRA2A (0.38) | HPGDHSD11B1HSD17B3SMN1; SMN2ELANE | |
| SCHEMBL28460446 | 0.72 | ADRB2 (0.41) | KDM4EALDH1A1LMNATP53MAPK1 | |
| SCHEMBL9037118 | 0.72 | POLB (0.37) | KDM4EALDH1A1HSD17B10MAPTTP53 | |
| SCHEMBL13802193 | 0.69 | HSD17B10 (0.39) | HSD17B10 | |
| SCHEMBL20108981 | 0.69 | ERN1 (0.62) | ERN1TLR2TLR1TLR6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066862-A1 | LUBRICATING COMPOSITIONS | SHELL INTERNATIONALE RESEARCH MAATSCHAPPIJ B.V. (NL) | 2010-06-17 | — | — | WO | disclosed |