Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | CDK4 | P11802 | 1/20 | 0.35 |
| ▸ | CCND1 | P24385 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | RXRB | P28702 | 1/20 | 0.33 |
| ▸ | RXRG | P48443 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034308 | 0.80 | CA1 (0.52) | NPSR1TSHRALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9161422 | 0.78 | KMT2A (0.38) | ALDH1A1MEN1KMT2ARAB9ASMN1; SMN2 | |
| SCHEMBL8799400 | 0.77 | MAOB (0.39) | MEN1KMT2ARXRARXRBRXRG | |
| SCHEMBL29690513 | 0.76 | TSHR (0.45) | TSHRALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL2737142 | 0.76 | TSHR (0.45) | TSHRALDH1A1MEN1KMT2ANPC1 | |
| SCHEMBL3417543 | 0.76 | ERN1 (0.43) | ALDH1A1NPC1SMN1; SMN2HPGDKDM4E | |
| SCHEMBL28460446 | 0.76 | ADRB2 (0.41) | ALDH1A1RAB9ASMN1; SMN2KDM4EDRD2 | |
| SCHEMBL9037118 | 0.76 | POLB (0.37) | NPSR1TSHRALDH1A1KMT2ASMN1; SMN2 | |
| SCHEMBL9034506 | 0.76 | ADRA2A (0.38) | MEN1KMT2ASMN1; SMN2HPGDDRD2 | |
| SCHEMBL13012364 | 0.74 | TSHR (0.43) | TSHRALDH1A1MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396698-A1 | MANUFACTURE OF ARYLOXYALDEHYDES. | ICI PLC (GB) | 1990-11-14 | — | — | EP | claimed |
| WO-1990004580-A1 | ARYLOXYALDEHYDES AND THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-03 | — | — | WO | claimed |
| CN-1034120-C | Pyridine derivatives | ZENECA LTD (GB) | 1997-02-26 | — | — | CN | disclosed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| EP-0396698-B1 | MANUFACTURE OF ARYLOXYALDEHYDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-23 | — | — | EP | disclosed |
| US-5169974-A | Process for manufacturing aryloxyaldehydes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-08 | — | — | US | disclosed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0396698-A1 | MANUFACTURE OF ARYLOXYALDEHYDES. | ICI PLC (GB) | 1990-11-14 | — | — | EP | disclosed |
| CN-1041942-A | Pyridine derivate | ICI PLC (GB) | 1990-05-09 | — | — | CN | disclosed |
| WO-1990004580-A1 | ARYLOXYALDEHYDES AND THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-03 | — | — | WO | disclosed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | disclosed |