Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGTR2 | P50052 | 7/20 | 0.43 |
| ▸ | ACE | P12821 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SLC6A1 | P30531 | 1/20 | 0.36 |
| ▸ | SLC6A11 | P48066 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034390 | 1.00 | AGTR2 (0.43) | AGTR2ACEKMT2ASLC6A1SLC6A11 | |
| SCHEMBL9035380 | 1.00 | AGTR2 (0.43) | AGTR2ACEKMT2ASLC6A1SLC6A11 | |
| SCHEMBL5492058 | 0.84 | HTRA1 (0.41) | AGTR2ACEKMT2A | |
| SCHEMBL9034973 | 0.81 | UCHL1 (0.33) | AGTR2ACEKMT2A | |
| SCHEMBL9032670 | 0.81 | UCHL1 (0.33) | AGTR2ACEKMT2A | |
| SCHEMBL9032678 | 0.81 | UCHL1 (0.33) | AGTR2ACEKMT2A | |
| SCHEMBL9033483 | 0.81 | SLC6A1 (0.35) | AGTR2SLC6A1SLC6A11 | |
| SCHEMBL9033488 | 0.81 | SLC6A1 (0.35) | AGTR2SLC6A1SLC6A11 | |
| SCHEMBL9034795 | 0.81 | SLC6A1 (0.35) | AGTR2SLC6A1SLC6A11 | |
| SCHEMBL5409304 | 0.80 | CA12 (0.38) | AGTR2ACEKMT2ASLC6A1SLC6A11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |