Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | KIF11 | P52732 | 1/20 | 0.31 |
| ▸ | TACR1 | P25103 | 1/20 | 0.31 |
| ▸ | PLA2G4A | P47712 | 2/20 | 0.30 |
| ▸ | PLA2G6 | O60733 | 1/20 | 0.30 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9032670 | 1.00 | UCHL1 (0.33) | UCHL1MCL1BCL2KIF11TACR1 | |
| SCHEMBL9032678 | 1.00 | UCHL1 (0.33) | UCHL1MCL1BCL2KIF11TACR1 | |
| SCHEMBL7138214 | 0.89 | UCHL1 (0.44) | UCHL1TACR1 | |
| SCHEMBL7165134 | 0.84 | ECE1 (0.38) | UCHL1CHRM3KMT2A | |
| SCHEMBL7139409 | 0.84 | ECE1 (0.38) | UCHL1CHRM3KMT2A | |
| SCHEMBL9035380 | 0.81 | AGTR2 (0.43) | AGTR2ACEKMT2A | |
| SCHEMBL9034394 | 0.81 | AGTR2 (0.43) | AGTR2ACEKMT2A | |
| SCHEMBL9034390 | 0.81 | AGTR2 (0.43) | AGTR2ACEKMT2A | |
| SCHEMBL8394546 | 0.76 | CHRM3 (0.34) | MCL1BCL2KIF11CHRM3 | |
| SCHEMBL7137592 | 0.74 | MMP2 (0.42) | AGTR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696593-A2 | Inhibitors of farnesyl protein transferase | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-02-14 | — | — | EP | disclosed |