Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 5/20 | 0.36 |
| ▸ | HTR1D | P28221 | 5/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | AHCY | P23526 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | HTR2C | P28335 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034486 | 1.00 | HTR1A (0.36) | HTR1AHTR1DCA2SSTR4AHCY | |
| SCHEMBL8879248 | 0.89 | HTR1A (0.38) | HTR1AHTR1DCA2HTR2AHTR2C | |
| SCHEMBL8921140 | 0.89 | HTR1A (0.38) | HTR1AHTR1DCA2HTR2AHTR2C | |
| SCHEMBL9033927 | 0.78 | CA2 (0.45) | HTR1AHTR1DCA2SSTR4 | |
| SCHEMBL8877007 | 0.76 | HTR1A (0.39) | HTR1AHTR1DCA2 | |
| SCHEMBL8995865 | 0.76 | HTR1A (0.39) | HTR1AHTR1DCA2 | |
| SCHEMBL9033661 | 0.74 | HTR1A (0.40) | HTR1ACA2 | |
| SCHEMBL21091993 | 0.70 | NR1D1 (0.39) | CA2 | |
| SCHEMBL5327408 | 0.69 | CA2 (0.52) | HTR1AHTR1DCA2SSTR4 | |
| SCHEMBL5327405 | 0.69 | CA2 (0.52) | HTR1AHTR1DCA2SSTR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0639192-B1 | (BENZODIOXAN, BENZOFURAN OR BENZOPYRAN)-ALKYLAMINO] ALKYL SUBSTITUTED GUANIDINES AS SELECTIVE VASCOCONSTRICTORS | JANSSEN PHARMACEUTICA NV (BE) | 1996-05-15 | — | — | EP | disclosed |