Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAD52 | P43351 | 1/20 | 0.51 |
| ▸ | HTR7 | P34969 | 2/20 | 0.50 |
| ▸ | HTR1D | P28221 | 6/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTR1B | P28222 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 2/20 | 0.46 |
| ▸ | HTR6 | P50406 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033694 | 0.93 | HTR1D (0.52) | RAD52HTR7HTR1DSLC6A4KDM4E | |
| SCHEMBL9033765 | 0.92 | HTR1D (0.49) | RAD52HTR7HTR1DHTR1ASLC6A4 | |
| SCHEMBL9034449 | 0.89 | SLC6A4 (0.49) | HTR1DHTR1ASLC6A4HTR1BMEN1 | |
| SCHEMBL9035807 | 0.87 | CYP1A2 (0.54) | RAD52HTR7HTR1DHTR1ASLC6A4 | |
| SCHEMBL9035794 | 0.87 | HTR1D (0.49) | HTR1DHTR1ASLC6A4KDM4EALDH1A1 | |
| SCHEMBL9033683 | 0.85 | SLC6A4 (0.64) | HTR7HTR1ASLC6A4DRD2HTR6 | |
| SCHEMBL9034427 | 0.85 | OPRM1 (0.57) | HTR7HTR1ASLC6A4KDM4EALDH1A1 | |
| SCHEMBL9033141 | 0.85 | HTR2A (0.47) | RAD52HTR7HTR1DSLC6A4KDM4E | |
| SCHEMBL9032917 | 0.83 | SLC6A4 (0.65) | HTR7HTR1ASLC6A4DRD2HTR6 | |
| SCHEMBL9051682 | 0.83 | KCNH2 (0.52) | HTR7HTR1ASLC6A4DRD2HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |