Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | HTR1A | P08908 | 5/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.47 |
| ▸ | HTR6 | P50406 | 2/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.46 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.46 |
| ▸ | GABRP | O00591 | 1/20 | 0.46 |
| ▸ | GABRD | O14764 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.46 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.46 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.46 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.46 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.46 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.46 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.46 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.46 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.46 |
| ▸ | GABRE | P78334 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034241 | 0.93 | HTR7 (0.45) | KCNH2HTR1ASLC6A4HTR6DRD2 | |
| SCHEMBL9033683 | 0.86 | SLC6A4 (0.64) | HTR1ASLC6A4HTR6DRD2HTR7 | |
| SCHEMBL9035807 | 0.86 | CYP1A2 (0.54) | HTR1ASLC6A4HTR6DRD2HTR7 | |
| SCHEMBL9034427 | 0.86 | OPRM1 (0.57) | HTR1ASLC6A4HTR6DRD2HTR7 | |
| SCHEMBL9033765 | 0.84 | HTR1D (0.49) | HTR1ASLC6A4HTR6DRD2HTR7 | |
| SCHEMBL9032917 | 0.84 | SLC6A4 (0.65) | HTR1ASLC6A4HTR6DRD2HTR7 | |
| SCHEMBL9034645 | 0.83 | RAD52 (0.51) | HTR1ASLC6A4HTR6DRD2HTR7 | |
| SCHEMBL9033610 | 0.83 | MEN1 (0.45) | SLC6A4HTR7 | |
| SCHEMBL9033713 | 0.82 | SLC6A4 (0.51) | HTR1ASLC6A4HTR6DRD2HTR7 | |
| SCHEMBL9034449 | 0.81 | SLC6A4 (0.49) | HTR1ASLC6A4DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |