Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | RAD52 | P43351 | 1/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9033765 | 0.93 | HTR1D (0.49) | HTR2AHTR7LMNAALDH1A1MAPT | |
| SCHEMBL9033694 | 0.92 | HTR1D (0.52) | HTR2AHTR7LMNAALDH1A1MAPT | |
| SCHEMBL9034575 | 0.90 | MEN1 (0.48) | HTR2AHTR7LMNAALDH1A1MAPT | |
| SCHEMBL9036825 | 0.88 | MEN1 (0.49) | HTR2AHTR7LMNAALDH1A1MAPT | |
| SCHEMBL9034357 | 0.86 | DRD2 (0.60) | HTR2AHTR7LMNAALDH1A1MAPT | |
| SCHEMBL9034110 | 0.86 | KDM4E (0.49) | HTR2AHTR7LMNAALDH1A1MAPT | |
| SCHEMBL9034645 | 0.85 | RAD52 (0.51) | HTR7LMNAALDH1A1MAPTKDM4E | |
| SCHEMBL9034780 | 0.84 | HTR1A (0.56) | HTR2AHTR7LMNAALDH1A1KDM4E | |
| SCHEMBL9034241 | 0.84 | HTR7 (0.45) | HTR2AHTR7MAPTKDM4ERAB9A | |
| SCHEMBL9034948 | 0.84 | KCNH2 (0.52) | HTR2AHTR7KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0722942-A1 | Indole piperidine derivatives | MERCK PATENT GmbH (DE) | 1996-07-24 | — | — | EP | disclosed |