Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | CTSB | P07858 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8698405 | 0.89 | HRH3 (0.39) | CTSLHRH3SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL9034551 | 0.86 | HRH3 (0.39) | HRH3SMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL9031818 | 0.84 | CTSL (0.44) | CTSLSMN1; SMN2CYP2C9CYP2C19CTSB | |
| SCHEMBL9032737 | 0.83 | CTSL (0.44) | CTSLSMN1; SMN2CYP2C9CYP2C19CTSB | |
| SCHEMBL9033091 | 0.83 | CTSL (0.46) | CTSLHRH3SMN1; SMN2MAPTCTSB | |
| SCHEMBL9034257 | 0.82 | SMN1; SMN2 (0.41) | SMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL9033818 | 0.81 | CTSL (0.45) | CTSLSMN1; SMN2MAPTCTSBCTSK | |
| SCHEMBL9033877 | 0.80 | SMN1; SMN2 (0.44) | SMN1; SMN2ALDH1A1MAPTCYP2C9KDM4E | |
| SCHEMBL9032671 | 0.79 | HRH3 (0.42) | HRH3SMN1; SMN2ALDH1A1MAPTHTT | |
| SCHEMBL9034654 | 0.78 | SLC6A2 (0.35) | CTSLSMN1; SMN2ALDH1A1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |