Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | PPID | Q08752 | 1/20 | 0.40 |
| ▸ | ANPEP | P15144 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9031818 | 0.86 | CTSL (0.44) | SMN1; SMN2ATMCYP2D6CYP2C9OPRK1 | |
| SCHEMBL9032737 | 0.85 | CTSL (0.44) | SMN1; SMN2ATMLMNACYP2D6CYP2C9 | |
| SCHEMBL9034257 | 0.84 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AMAPTOPRD1LMNA | |
| SCHEMBL9034551 | 0.83 | HRH3 (0.39) | SMN1; SMN2L3MBTL1MAPTOPRD1LMNA | |
| Hydrochloric Acid SCHEMBL9033421 | 0.81 | SMN1; SMN2 (0.41) | SMN1; SMN2KMT2AL3MBTL1OPRD1LMNA | |
| SCHEMBL9034647 | 0.80 | CTSL (0.38) | SMN1; SMN2L3MBTL1MAPTKDM4EALDH1A1 | |
| SCHEMBL9033094 | 0.77 | ITGB3 (0.45) | SMN1; SMN2KDM4EALDH1A1CYP2D6CYP2C9 | |
| SCHEMBL9033091 | 0.76 | CTSL (0.46) | SMN1; SMN2MAPTATMLMNAOPRK1 | |
| SCHEMBL9034601 | 0.76 | CTSL (0.40) | SMN1; SMN2KMT2AATMLMNACYP2D6 | |
| SCHEMBL9033441 | 0.75 | HRH3 (0.43) | SMN1; SMN2KMT2AL3MBTL1MAPTOPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0696586-A1 | SERINE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1996-02-14 | — | — | EP | disclosed |