Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | XBP1 | P17861 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | TERT | O14746 | 1/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL809474 | 0.78 | HPGD (0.36) | HSD11B1MAPTMEN1KMT2AHTT | |
| SCHEMBL7937564 | 0.75 | SLC6A4 (0.45) | HSD11B1MAPTMEN1KMT2AHTT | |
| SCHEMBL23060729 | 0.73 | ALDH1A1 (0.39) | HSD11B1MAPTMEN1KMT2AHTT | |
| SCHEMBL11799983 | 0.72 | LMNA (0.31) | HTT | |
| SCHEMBL12227381 | 0.69 | KDM4E (0.40) | MEN1KMT2ASMN1; SMN2KDM4E | |
| SCHEMBL12824585 | 0.69 | SLC22A12 (0.51) | MAPTMEN1KMT2AHTTALDH1A1 | |
| SCHEMBL186764 | 0.69 | RAB9A (0.42) | HSD11B1MAPTMEN1KMT2AHTT | |
| SCHEMBL7940607 | 0.67 | ALDH1A1 (0.61) | MAPTHTTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7938138 | 0.66 | ALDH1A1 (0.36) | MAPTMEN1KMT2AHTTNPC1 | |
| SCHEMBL29254129 | 0.66 | POLB (0.38) | HSD11B1MAPTMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0396698-A1 | MANUFACTURE OF ARYLOXYALDEHYDES. | ICI PLC (GB) | 1990-11-14 | — | — | EP | claimed |
| WO-1990004580-A1 | ARYLOXYALDEHYDES AND THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-03 | — | — | WO | claimed |
| CN-1034120-C | Pyridine derivatives | ZENECA LTD (GB) | 1997-02-26 | — | — | CN | disclosed |
| EP-0365328-B1 | Pyridine derivatives | ZENECA LTD (GB) | 1996-04-03 | — | — | EP | disclosed |
| EP-0396698-B1 | MANUFACTURE OF ARYLOXYALDEHYDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1993-06-23 | — | — | EP | disclosed |
| US-5169974-A | Process for manufacturing aryloxyaldehydes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-12-08 | — | — | US | disclosed |
| US-5053415-A | Antiischemic, antiinflammatory, antiarthritic agents, cardiovascular disorders | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-10-01 | — | — | US | disclosed |
| EP-0396698-A1 | MANUFACTURE OF ARYLOXYALDEHYDES. | ICI PLC (GB) | 1990-11-14 | — | — | EP | disclosed |
| CN-1041942-A | Pyridine derivate | ICI PLC (GB) | 1990-05-09 | — | — | CN | disclosed |
| WO-1990004580-A1 | ARYLOXYALDEHYDES AND THEIR MANUFACTURE | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-05-03 | — | — | WO | disclosed |
| EP-0365328-A2 | Pyridine derivatives | ZENECA LIMITED (GB) | 1990-04-25 | — | — | EP | disclosed |