Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.53 |
| ▸ | CHRNB2 | P17787 | 4/20 | 0.47 |
| ▸ | CHRNA4 | P43681 | 4/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824524 | 0.76 | SCN9A (0.55) | MEN1MAPTKMT2ADRD2DRD3 | |
| SCHEMBL23432691 | 0.75 | CHRNB2 (0.56) | CHRNB2CHRNA4 | |
| SCHEMBL9976279 | 0.74 | TRPV6 (0.47) | MEN1MAPTKMT2ATRPV6CHRNB2 | |
| SCHEMBL28396664 | 0.72 | ADRB1 (0.71) | DRD2DRD4DRD3ADRB1 | |
| SCHEMBL27333031 | 0.72 | HTT (0.44) | MEN1MAPTKMT2ATRPV6 | |
| SCHEMBL161236 | 0.71 | CHRNB2 (0.76) | CHRNB2CHRNA4 | |
| SCHEMBL19212308 | 0.71 | ADRB1 (0.59) | MAPTDRD2DRD4DRD3ADRB1 | |
| SCHEMBL11544331 | 0.71 | CHRNB2 (0.76) | CHRNB2CHRNA4 | |
| SCHEMBL29959593 | 0.71 | CHRNB2 (0.76) | CHRNB2CHRNA4 | |
| SCHEMBL21987008 | 0.71 | MEN1 (1.00) | MEN1MAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0719773-A1 | IMIDAZOLIDINONE DERIVATIVE, ACID-ADDITION SALT THEREOF, AND REMEDY FOR SENILE DEMENTIA | KYORIN PHARMACEUTICAL CO., LTD. (JP) | 1996-07-03 | — | — | EP | disclosed |