Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | HTR1A | P08908 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.49 |
| ▸ | EGFR | P00533 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9036283 | 0.92 | ALDH1A1 (0.52) | ALDH1A1KMT2AGFERHTR1ASIGMAR1 | |
| SCHEMBL9036253 | 0.84 | SIGMAR1 (0.52) | ALDH1A1KMT2AGFERHTR1ASIGMAR1 | |
| SCHEMBL9035245 | 0.83 | KMT2A (0.62) | ALDH1A1KMT2AGFERHTR1ASIGMAR1 | |
| SCHEMBL9035090 | 0.75 | KMT2A (0.59) | ALDH1A1KMT2AGFERHTR1ASIGMAR1 | |
| SCHEMBL12123772 | 0.75 | ALDH1A1 (0.83) | ALDH1A1KMT2AEGFRMAPTLMNA | |
| SCHEMBL9034385 | 0.75 | ALDH1A1 (0.61) | ALDH1A1KMT2AHTR1ASIGMAR1MAPT | |
| SCHEMBL9035205 | 0.75 | SIGMAR1 (0.54) | KMT2AHTR1ASIGMAR1SMN1; SMN2RAB9A | |
| SCHEMBL2725965 | 0.75 | KMT2A (0.90) | ALDH1A1KMT2AGFERHTR1ASIGMAR1 | |
| SCHEMBL10507206 | 0.75 | ALDH1A1 (0.96) | ALDH1A1KMT2AGFERHTR1ASIGMAR1 | |
| SCHEMBL31093179 | 0.74 | KMT2A (0.71) | ALDH1A1KMT2AGFERHTR1ASIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | claimed |
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | disclosed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | disclosed |