Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SOD1 | P00441 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9034385 | 0.81 | ALDH1A1 (0.61) | KMT2AALDH1A1HTR1ALMNAMAPT | |
| SCHEMBL9035205 | 0.81 | SIGMAR1 (0.54) | KMT2AMEN1HTR1AHTTTSHR | |
| SCHEMBL9035090 | 0.81 | KMT2A (0.59) | KMT2AMEN1ALDH1A1GFERHTR1A | |
| SCHEMBL9035245 | 0.80 | KMT2A (0.62) | KMT2AALDH1A1GFERHTR1ALMNA | |
| SCHEMBL9036283 | 0.78 | ALDH1A1 (0.52) | KMT2AALDH1A1GFERHTR1ALMNA | |
| SCHEMBL9035735 | 0.77 | ALDH1A1 (0.42) | KMT2AMEN1ALDH1A1GFERLMNA | |
| SCHEMBL9036253 | 0.76 | SIGMAR1 (0.52) | KMT2AMEN1ALDH1A1GFERHTR1A | |
| SCHEMBL4472849 | 0.74 | ALDH1A1 (0.70) | KMT2AHDAC1HDAC8ALDH1A1GFER | |
| SCHEMBL10605457 | 0.74 | RAB9A (0.61) | KMT2AMEN1HDAC1HDAC8ALDH1A1 | |
| SCHEMBL11763488 | 0.74 | RAB9A (0.61) | KMT2AMEN1HDAC1HDAC8ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0411775-B1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZET (HU) | 1996-03-13 | — | — | EP | disclosed |
| US-5096902-A | Cerebral antihypoxic action, senile dememtia, Alzheimer's, cognitive functions | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 1992-03-17 | — | — | US | disclosed |
| EP-0411775-A1 | Heterocyclic compounds containing nitrogen and sulfur, processes for their preparation and pharmaceutical compositions thereof | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 1991-02-06 | — | — | EP | disclosed |