Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP14 | Q460N5 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | PDE1A | P54750 | 2/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 2/20 | 0.31 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.31 |
| ▸ | PIK3R2 | O00459 | 8/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | STAT6 | P42226 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9035190 | 0.70 | PARP1 (0.41) | LMNA | |
| SCHEMBL9034379 | 0.68 | ALDH1A1 (0.37) | SMN1; SMN2 | |
| SCHEMBL9035248 | 0.68 | LMNA (0.33) | LMNA | |
| SCHEMBL9035474 | 0.67 | GRM5 (0.35) | LMNASMN1; SMN2 | |
| SCHEMBL7265551 | 0.66 | ATM (0.45) | — | |
| SCHEMBL6139581 | 0.65 | PARP1 (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL9035198 | 0.63 | PARP1 (0.33) | — | |
| SCHEMBL6139222 | 0.60 | PARP1 (0.44) | LMNA | |
| Ethylene SCHEMBL6511634 | 0.58 | PARP1 (0.42) | LMNA | |
| SCHEMBL6503471 | 0.57 | SMN1; SMN2 (0.34) | LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0405442-B1 | 4,5-Dihydro-6H-imidazo[4,5,1-ij]quinolin-6-one-6-oxime-O-sulfonic acid derivatives | MOCHIDA PHARM CO LTD (JP) | 1996-09-04 | — | — | EP | claimed |