Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 6/20 | 0.54 |
| ▸ | SETD7 | Q8WTS6 | 3/20 | 0.52 |
| ▸ | HTR1A | P08908 | 3/20 | 0.52 |
| ▸ | DRD2 | P14416 | 4/20 | 0.49 |
| ▸ | HTR2A | P28223 | 3/20 | 0.49 |
| ▸ | HTR2B | P41595 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | HTR7 | P34969 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | HTR2C | P28335 | 3/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.49 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7218929 | 0.99 | SIGMAR1 (0.53) | SIGMAR1SETD7HTR1ADRD2HTR2A | |
| SCHEMBL9373592 | 0.93 | DRD2 (0.58) | SIGMAR1SETD7HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7212577 | 0.92 | DRD2 (0.57) | SIGMAR1SETD7HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7217662 | 0.91 | SETD7 (0.57) | SIGMAR1SETD7HTR1ADRD2HTR2A | |
| SCHEMBL9035949 | 0.90 | SETD7 (0.57) | SIGMAR1SETD7HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7218913 | 0.89 | KMT2A (0.57) | SIGMAR1SETD7HTR1ADRD2HTR2A | |
| SCHEMBL9035086 | 0.88 | SETD7 (0.54) | SIGMAR1SETD7HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL7218948 | 0.87 | SETD7 (0.53) | SIGMAR1SETD7HTR1ADRD2HTR2A | |
| Hydrochloric Acid SCHEMBL9034034 | 0.82 | SETD7 (0.59) | SETD7HTR1ADRD2HTR2AHTR2B | |
| Cyproheptadine SCHEMBL18344553 | 0.82 | HTR1A (0.66) | SIGMAR1SETD7HTR1ADRD2HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0371805-B1 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO KK (JP) | 1996-06-26 | — | — | EP | claimed |
| EP-0371805-A2 | Piperidine derivatives and hypotensives containing the same | AJINOMOTO CO., INC. (JP) | 1990-06-06 | — | — | EP | claimed |