SCHEMBL9035682

SCHEMBL9035682

[CH2]C(C)Cc1ncccn1

nearest known ligand 0.30

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2948062 0.79 KDM4E (0.39) KDM4E
SCHEMBL1331897 0.76 APLNR (0.39) —
SCHEMBL22092989 0.75 SLC6A2 (0.44) —
SCHEMBL15255480 0.75 LMNA (0.35) KDM4E
SCHEMBL18647938 0.75 TRPA1 (0.31) KDM4E
SCHEMBL1331883 0.75 NPC1 (0.33) —
SCHEMBL1333639 0.75 APLNR (0.37) —
SCHEMBL9038056 0.73 SORD (0.30) KDM4E
SCHEMBL9318794 0.73 GRIN2D (0.56) —
SCHEMBL4685897 0.73 GRIN2D (0.56) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0450066-B1 CARBOSTYRIL DERIVATIVES OTSUKA PHARMA CO LTD (JP) 1996-09-11 — — EP disclosed
US-5401740-A FOR INHIBITING PLATELET AGGREGATION OTSUKA PHARMACEUTICAL CO. (JP) 1995-03-28 — — US disclosed
US-5227381-A Anticoagulant OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1993-07-13 — — US disclosed
EP-0450066-A1 CARBOSTYRIL DERIVATIVES OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1991-10-09 — — EP disclosed
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