Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | FLT3 | P36888 | 5/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | GPR39 | O43194 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.33 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.33 |
| ▸ | NRAS | P01111 | 1/20 | 0.33 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037416 | 0.83 | CYP1A2 (0.45) | RAB9AKDM4EALDH1A1NPSR1NPC1 | |
| SCHEMBL11640848 | 0.83 | POLB (0.44) | POLBRAB9AFLT3KDM4EALDH1A1 | |
| SCHEMBL9595441 | 0.81 | RXFP1 (0.41) | RAB9AFLT3KDM4EALDH1A1NPSR1 | |
| SCHEMBL12998315 | 0.77 | TGFBR1 (0.48) | POLBTGFBR1 | |
| SCHEMBL9037112 | 0.74 | IRAK4 (0.46) | RAB9AFLT3KDM4EALDH1A1NPSR1 | |
| SCHEMBL28041698 | 0.70 | POLB (0.54) | POLBRAB9AFLT3ALDH1A1NPC1 | |
| Bromide SCHEMBL3016136 | 0.69 | POLB (0.50) | POLBRAB9AFLT3KDM4EALDH1A1 | |
| SCHEMBL9037089 | 0.69 | GABRG2 (0.56) | RAB9AFLT3KDM4EALDH1A1NPSR1 | |
| SCHEMBL16404632 | 0.67 | POLB (0.56) | POLBRAB9AFLT3ALDH1A1NPC1 | |
| SCHEMBL3325146 | 0.67 | POLB (0.51) | POLBRAB9AFLT3NPC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0385634-B1 | Process for producing pyrido[1,2-a] pyrimidine derivative | WAKO PURE CHEM IND LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| WO-1993016070-A1 | 3-(PYRIDYLAMINO)-2-(1H^_-TETRAZOL-5-YL)-ACRYLNITRILES AND A PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |
| US-5081243-A | Process for producing 3-tetrazolyl pyrido[1,2-a]pyrimidine derivatives | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| EP-0385634-A2 | Process for producing pyrido[1,2-a] pyrimidine derivative | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-09-05 | — | — | EP | disclosed |