Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 2/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.40 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.40 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.40 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.40 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9597156 | 0.81 | KDM4E (0.49) | IRAK4RAB9AKDM4ENPC1ALDH1A1 | |
| SCHEMBL9037089 | 0.78 | GABRG2 (0.56) | RAB9ANPSR1KDM4ENPC1RXFP1 | |
| SCHEMBL9037416 | 0.75 | CYP1A2 (0.45) | RAB9ANPSR1KDM4ENPC1RXFP1 | |
| SCHEMBL2016621 | 0.75 | NPSR1 (0.46) | IRAK4RAB9ANPSR1KDM4ENPC1 | |
| SCHEMBL9595441 | 0.74 | RXFP1 (0.41) | RAB9ANPSR1KDM4ENPC1RXFP1 | |
| SCHEMBL9035966 | 0.74 | POLB (0.43) | IRAK4RAB9ANPSR1KDM4ENPC1 | |
| Hydrochloric Acid SCHEMBL30318663 | 0.74 | NPSR1 (0.45) | IRAK4RAB9ANPSR1KDM4ENPC1 | |
| SCHEMBL9038833 | 0.73 | KDM4E (0.45) | RAB9ANPSR1KDM4ENPC1FLT3 | |
| SCHEMBL9600108 | 0.73 | RAB9A (0.40) | RAB9AKDM4EALDH1A1HPGDCASP1 | |
| SCHEMBL3313454 | 0.69 | MIF (0.53) | IRAK4RAB9ANPSR1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2289569-A | — | — | None | — | — | JP | disclosed |
| EP-0385634-B1 | Process for producing pyrido[1,2-a] pyrimidine derivative | WAKO PURE CHEM IND LTD (JP) | 1996-04-24 | — | — | EP | disclosed |
| WO-1993016076-A1 | 3-(1H^_-TETRAZOL-5-YL)-4H^_-PYRIDO[1,2-A^_]PYRIMIDINE-4-ONES, PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME AND THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |
| WO-1993016070-A1 | 3-(PYRIDYLAMINO)-2-(1H^_-TETRAZOL-5-YL)-ACRYLNITRILES AND A PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |
| US-5081243-A | Process for producing 3-tetrazolyl pyrido[1,2-a]pyrimidine derivatives | WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) | 1992-01-14 | — | — | US | disclosed |
| JP-H02289569-A | NEW PRODUCTION OF PYRIDO(1,2-A)PYRIMIDINE DERIVATIVE | WAKO PURE CHEM IND LTD | 1990-11-29 | — | — | JP | disclosed |
| EP-0385634-A2 | Process for producing pyrido[1,2-a] pyrimidine derivative | WAKO PURE CHEMICAL INDUSTRIES LTD (JP) | 1990-09-05 | — | — | EP | disclosed |