Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.41 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.35 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9037416 | 0.83 | CYP1A2 (0.45) | RXFP1RAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL9035966 | 0.81 | POLB (0.43) | RXFP1RAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL3756838 | 0.77 | TGFBR1 (0.46) | RXFP1MAP3K14PIK3CAMTORTGFBR1 | |
| SCHEMBL9037112 | 0.74 | IRAK4 (0.46) | RXFP1RAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL15288730 | 0.71 | MKNK1 (0.52) | MAP3K14PIK3CAMTORTRIM24TRIM33 | |
| SCHEMBL3029604 | 0.70 | MAP3K14 (0.49) | RXFP1MAP3K14PIK3CAMTORTRIM24 | |
| SCHEMBL9037089 | 0.69 | GABRG2 (0.56) | RXFP1RAB9AKDM4ENPC1NPSR1 | |
| SCHEMBL15288389 | 0.68 | PIK3CA (0.46) | RXFP1MAP3K14PIK3CAMTORTRIM24 | |
| SCHEMBL12998303 | 0.67 | PIK3CA (0.47) | MAP3K14PIK3CAMTORTRIM24TRIM33 | |
| SCHEMBL22125606 | 0.67 | MAP3K14 (0.50) | MAP3K14RAB9APIK3CAMTORTRIM24 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1993016070-A1 | 3-(PYRIDYLAMINO)-2-(1H^_-TETRAZOL-5-YL)-ACRYLNITRILES AND A PROCESS FOR THE PREPARATION THEREOF | CHINOIN GYÓGYSZER- ÉS VEGYÉSZETI TERMÉKEK GYÁRA RT. (HU) | 1993-08-19 | — | — | WO | disclosed |