Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | CASP1 | P29466 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.53 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.53 |
| ▸ | S1PR1 | P21453 | 8/20 | 0.51 |
| ▸ | S1PR3 | Q99500 | 6/20 | 0.51 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.51 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.50 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.50 |
| ▸ | CNR1 | P21554 | 2/20 | 0.49 |
| ▸ | CNR2 | P34972 | 2/20 | 0.49 |
| ▸ | DRD2 | P14416 | 2/20 | 0.48 |
| ▸ | DRD4 | P21917 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7475398 | 0.92 | S1PR1 (0.52) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL58833 | 0.91 | LMNA (0.61) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL8733409 | 0.91 | LMNA (0.61) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL6200177 | 0.91 | LMNA (0.61) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL7465256 | 0.91 | LMNA (0.61) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL6199890 | 0.90 | MEN1 (0.59) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL7329668 | 0.87 | LMNA (0.65) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL7321345 | 0.87 | LMNA (0.65) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL1353239 | 0.87 | ALDH1A1 (0.63) | MEN1USP2ALDH1A1LMNACYP3A4 | |
| SCHEMBL6324073 | 0.87 | LMNA (0.55) | MEN1USP2ALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0450066-B1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMA CO LTD (JP) | 1996-09-11 | — | — | EP | disclosed |
| US-5401740-A | FOR INHIBITING PLATELET AGGREGATION | OTSUKA PHARMACEUTICAL CO. (JP) | 1995-03-28 | — | — | US | disclosed |
| US-5227381-A | Anticoagulant | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1993-07-13 | — | — | US | disclosed |
| EP-0450066-A1 | CARBOSTYRIL DERIVATIVES | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1991-10-09 | — | — | EP | disclosed |